Research output

Publications

Selected and peer-reviewed research contributions in mathematical modelling, epidemic dynamics, medical statistics and health technology assessment.

Mathematical modelling · Epidemiology · Medical statistics · HTA

2026

Methotrexate’s effect on cells and adalimumab immunogenicity in axial spondyloarthritis: A mathematical study

Sottile, S., Paul, C., Audo, R., Rispens, T., Mulleman, D. and Rashkov, P.

PLOS Computational Biology, 22(9), e1014740.

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2025

Antibody Kinetics of Immunological Memory in SARS-CoV-2-Vaccinated Healthcare Workers—The ORCHESTRA Project

Seyedi, S., Sottile, S., Abedini, M., Boffetta, P., Violante, F.S., Lodi, V., De Palma, G., Sala, E., Mauro, M., Rui, F., et al.

Vaccines, 13(6), 611.

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2025

Health Technology Assessment del vaccino antinfluenzale quadrivalente adiuvato Fluad Tetra®: update

Calabrò, G.E. et al.; contribution by Rizzo, C., Sottile, S., Di Serafino, F. and Pugliese, A., Chapter 5: “Valutazione economica dell’introduzione del vaccino aQIV nella popolazione italiana di età superiore ai 60 anni”.

Journal of Preventive Medicine and Hygiene, 66(1 Suppl. 2), E1–E56.

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2025

A minimal model for multigroup adaptive SIS epidemics

Achterberg, M.A., Sensi, M. and Sottile, S.

Chaos: An Interdisciplinary Journal of Nonlinear Science, 35(3).

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2024

A geometric analysis of the SIRS compartmental model with fast information and misinformation spreading

Bulai, I.M., Sensi, M. and Sottile, S.

Chaos, Solitons & Fractals, 185, 115104.

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2024

A geometric analysis of the SIRS model with secondary infections

Kaklamanos, P., Pugliese, A., Sensi, M. and Sottile, S.

SIAM Journal on Applied Mathematics, 84(2), 661–686.

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2024

A geometric analysis of the impact of large but finite switching rates on vaccination evolutionary games

Della Marca, R., d’Onofrio, A., Sensi, M. and Sottile, S.

Nonlinear Analysis: Real World Applications, 75, 103986.

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2024

A survey on Lyapunov functions for epidemic compartmental models

Cangiotti, N., Capolli, M., Sensi, M. and Sottile, S.

Bollettino dell’Unione Matematica Italiana, 17, 241–257.

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2023

Global stability of multi-group SAIRS epidemic models

Ottaviano, S., Sensi, M. and Sottile, S.

Mathematical Methods in the Applied Sciences, 46(16), 14045–14071.

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2022

Health Technology Assessment: a value-based tool for the evaluation of healthcare technologies. Reassessment of the cell-culture-derived quadrivalent influenza vaccine: Flucelvax Tetra® 2.0

Calabrò, G.E. et al.; contribution by Rizzo, C., Saraceno, G., Sottile, S., Abreha, F.M. and Pugliese, A., Chapter 5.

Journal of Preventive Medicine and Hygiene, 63(4 Suppl. 1), E1–E138.

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2022

An Economic Evaluation of the Adjuvanted Quadrivalent Influenza Vaccine Compared with Standard-Dose Quadrivalent Influenza Vaccine in the Spanish Older Adult Population

Fochesato, A., Sottile, S., Pugliese, A., Márquez-Peláez, S., Toro-Diaz, H., Gani, R., Alvarez, P. and Ruiz-Aragón, J.

Vaccines, 10, 1360.

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2022

How network properties and epidemic parameters influence stochastic SIR dynamics on scale-free random networks

Sottile, S., Kahramanoğulları, O. and Sensi, M.

Journal of Simulation, 18(2), 206–219.

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2022

Global stability of SAIRS epidemic models

Ottaviano, S., Sensi, M. and Sottile, S.

Nonlinear Analysis: Real World Applications, 26, 103501.

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2021

Health Technology Assessment (HTA) of the introduction of influenza vaccination for Italian children

Boccalini, S. et al.; contribution by Rizzo, C., Sottile, S. and Pugliese, A., Chapter 6: “Valutazione economica dell’introduzione del vaccino antinfluenzale vivo attenuato (Fluenz Tetra®) nella popolazione giovanile italiana (2–6 anni)”.

Journal of Preventive Medicine and Hygiene, 62(2 Suppl. 1), E1–E128.

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2020

Time-varying epidemic transmission in heterogeneous networks and applications to measles

Sottile, S. and Liu, X.

Journal of Biological Systems, 28(4), 1–26.

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